DUB activity profiling Archives - Page 3 of 5

Biotin-ANP-Ub-PA

a potent and specific inhibitor of deubiquitylating enzymes (DUBs), labeled on the N-terminus with biotin and containing the UV cleavable 3-amino-3-(2-nitrophenyl)propanoic acid (ANP) linker, allowing for UV mediated cleavage of…

UbiQ-077

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K720 Nedd8-cullin1 (711-730)-FP

a class II fluorescence polarization HTS reagent based on the cullin-1 (711-730) polypeptide, modified on the N-terminus with a 5-carboxytetramethylrhodamine and mononeddylated at K720 via a native isopeptide bond

UbiQ-080

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K720 Nedd8-cullin1 (715-725)-FP

a class II fluorescence polarization HTS reagent based on the cullin-1 (715-725) polypeptide, modified on the N-terminus with a 5-carboxytetramethylrhodamine and mononeddylated at K720 via a native isopeptide bond

UbiQ-096

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Ub-VS

an activity-based probe for deubiquitinating enzymes (DUBs)

productsheet

UbiQ-108

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(Biotin-Ahx-Ub)-(Cys-Ahx-Ub) K48 linked

a native K48 linked di-ubiquitin, modified with biotin on the N-terminus of the distal Ub and cysteine on the N-terminus of the proximal Ub

UbiQ-119

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Ub-Rh110MP

a quenched, fluorescent substrate for ubiquitin proteases, releasing a brighter Rh110MP dye upon DUB cleavage than UbRh110Gly

productsheet

UbiQ-126

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Ac-ISG15prox-Rh110MP

a quenched, fluorescent substrate for ISG15 proteases based on the proximal part of (mouse) ISG15

productsheet

UbiQ-127

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Biotin-Ahx-H2B(106-125) K120Ub

an H2B(106-125) peptide which is modified at K120 via a native isopeptide bond with ubiquitin and modified on the N-terminus with biotin

productsheet

UbiQ-150

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Biotin-Ahx-SUMO2-VME

a potent, irreversible and specific activity-based probe for SUMO proteases, labeled with biotin on the N-terminus

productsheet

UbiQ-156

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Biotin-Ahx-SUMO2-PA

an activity-based probe for SUMO proteases, tagged with biotin on the N-terminus

productsheet

UbiQ-168

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H2A(5-21) K13Ub

an H2A(5-21) peptide which is modified at K13 via a native isopeptide bond with ubiquitin

productsheet

UbiQ-172

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Ub K6C

ubiquitin (Ub) in which Lys6 has been mutated to a cysteine residue

productsheet

UbiQ-174

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