Our total synthesis based technology platform allows us to prepare ubiquitin and ubiquitin like protein reagents with various modifications:
assay reagents, probes, chains and ubiquitinated peptides
ubiquitin and ubiquitin-like proteins e.g. Nedd8, SUMO, ISG15 etc
electrophiles (warheads), peptides (substrate context), tags, unnatural amino acids
price & timelines
prices are on a project basis and bulk preparation (starting at 2 mg)
- 6 – 8 weeks lead time for most projects
over the years, we have developed a large number of custom probes, assay reagents and ubiquitinated peptides for the top 10 Pharma, biotechs and academic institutions: DUB specific assay reagents probes, HTRF assays, custom electrophiles, assays reagents and probes with substrate context.
we also co-developed an antibody for yeast K123 Ub-H2B.
want to know more?
Please contact us at email@example.com to discuss your project and/or receive a detailed quote.
- Peptide pull-down assays with monoubiquitinated H2B & PTEN based peptides: R. Kessler et al. “dDsk2 regulates H2Bub1 and RNA polymerase II pausing at dHP1c complex target genes“. Nat. Commun. 2015, 6, article number 7049. Doi: 10.1038/ncomms8049