Ac-ISG15prox-Rh110MP

a quenched, fluorescent substrate for ISG15 proteases based on the proximal part of (mouse) ISG15

productsheet

code UbiQ-127 Category Tags ,
product UbiQ-127 Category Tags ,

Additional information

Weight 0.005 kg
aliquot size

bulk

Applications

,

target

source

human sequence, synthetic

shipping

purity

molecular weight

storage

sample preparation

For detailed sample preparation see product sheet.

regulatory statement

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300.00

Description

Ac-ISG15prox-Rh110MP (UbiQ-127) is a new type of quenched, fluorescent substrate for ISG15 proteases based on the proximal part of (mouse) ISG15. Cleavage of the amide bond between the C-terminal Gly and rhodamine110 moiety releases the highly fluorescent Rh110-morpholinecarbonyl (Rh110MP). [Terentyeva et al.]

• keep the excellent properties of the classic ubiquitin-Rh110 substrate [Hassiepen et al.]
• with high fluorescence intensity after proteolytic cleavage

Additional information

Weight 0.005 kg
aliquot size

bulk

Applications

,

target

source

human sequence, synthetic

shipping

purity

molecular weight

storage

sample preparation

For detailed sample preparation see product sheet.

regulatory statement

Terentyeva et al. Bioconj. Chem. 2011, 22, 1932.
https://www.ncbi.nlm.nih.gov/pubmed/21905728

Hassiepen et al. Analyt. Biochem. 2007, 371, 201.
https://www.ncbi.nlm.nih.gov/pubmed/17869210