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blogs

Reagents for your SARS-CoV-2 research

  Reagents for your SARS-CoV-2 research  The SARS-CoV-2 coronavirus encodes a papain-like cysteine protease PLpro (NSP3) that cleaves the viral polyprotein, removes ubiquitin-like ISG15 protein modifications and (with lower activity) Lys48-linked polyubiquitin chains. As PLPro is essential for SARS-CoV-2 replication, it represents a promising target for...

A collaborative effort between scientists at UbiQ, Genentech, Boston Biochem (Bio-Techne) and Stanford University.

  28 January 2019 Bio-orthogonally tagged activity-based probes forproteomics of deubiquitinating enzymes   A recent paper in Nature Communications describes a collaborative effort between scientists at UbiQ, Genentech, Boston Biochem (Bio-Techne) and Stanford University (1). Here a reactive-site-centric chemoproteomics protocol is presented...

where to meet us

BIO-Europe 2018

UbiQ will attend BIO-Europe 2018. November 5 - 7, 2018 Amsterdam, Denmark Contact: Alfred Nijkerk BIO-Europe: https://ebdgroup.knect365.com/bioeurope/

BIO-Europe Spring 2018

UbiQ will attend BIO-Europe Spring. March 12 - 14, 2018 Amsterdam, the Netherlands Contact: Alfred Nijkerk BIO-Europe: https://ebdgroup.knect365.com/bioeurope-spring/

Bio-Europe 2017

UbiQ will attend BIO-Europe. November 6 - 8, 2017 Berlin, Germany Contact: Alfred Nijkerk BIO-Europe: https://ebdgroup.knect365.com/bioeurope/

EMBO conference on Ubiquitin 2017

September 15 - 19, 2017 Cavtat, Croatia Ubiquitin and SUMO: From molecular mechanisms to system-wide responses Contact: Boris Rodenko (VP Translational Drug Discovery) / Alfred Nijkerk (CEO) / Oana Onciu (Scientist) More info conference: http://meetings.embo.org/event/17-ubiquitin

publications

Collaborative research between the University of York, University of Glasgow and UbiQ looks into the (essential) roles of ubiquitin proteases (DUBs) and ubiquitin conjugation in Leishmania parasites.

21st Royal Society of Chemistry - Medicinal Chemistry Symposium, 13 - 15 September 2021, Cambridge UK. Poster title: A ubiquitin activating enzyme as a novel therapeutic target for leishmaniasis. Daniel Harris (1), Dr Mads Gabrielson (2),...