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K720 Nedd8-cullin1 (715-725)-FP
a class II fluorescence polarization HTS reagent based on the cullin-1 (715-725) polypeptide, modified on the N-terminus with a 5-carboxytetramethylrhodamine and mononeddylated at K720 via a native isopeptide bond
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Ubiquitin
wild-type ubiquitin (Ub), synthesized by total chemical synthesis.
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NEDD8
wild-type Nedd8 which has been synthesized by total chemical synthesis
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Ub-Dha
an activity-based probe for Ub E1, E2 and (HECT/RBR) E3 ligases
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Biotin-Ahx-Ub-Dha
an activity-based probe for Ub E1, E2 and (HECT/RBR) E3 ligases, labeled with biotin on the N-terminus
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His6-Ahx-Ahx-Ub-Dha
an activity-based probe for Ub E1, E2 and (HECT/RBR) E3 ligases, labeled with His6 on the N-terminus
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Cy5-Ub-Dha
an activity-based probe for Ub E1, E2 and (HECT/RBR) E3 ligases, labeled with a Cy5 dye on the N-terminus
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Nedd8-Dha
an activity-based probe for Nedd8 E1, E2 and E3 enzymes
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Biotin-Ahx-Nedd8-Dha
an activity-based probe for Nedd8 E1, E2 and E3 enzymes, labeled with biotin on the N-terminus
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Ub-VS
a potent and specific inhibitor of deubiquitinating enzymes (DUBs)
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Ub pSer57
ubiquitin, phosphorylated on Ser57
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K63 diUb-PA
a potent, irreversible and specific inhibitor based on K63-linked diUb targeting the S2 pocket of deubiquitinating enzymes (DUBs)
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