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Ub-VME
a potent, irreversible and specific inhibitor of deubiquitylating enzymes (DUBs)
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Me4BodipyFL-Ahx3Leu3VS | fluorescent proteasome probe
a fluorescent proteasome activity probe that allows for accurate profiling of proteasomal activity in cell lysates, intact cells, and murine and human patient-derived material, with high sensitivity using SDS-PAGE
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Mca-KKVAPYPME-Dap(Dnp)–NH2 | proteasome activity assay reagent
an LF2 peptide based fluorogenic proteasome assay reagent for monitoring 26S proteasome, or ClpP protease activity
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Ub photoLeu8
a crosslinking reagent based on ubiquitin in which Leu8 is replaced by the photoreactive analog photoleucine (photoLeu)
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Ub photoLeu73
a crosslinking reagent based on ubiquitin in which Leu73 is replaced by the photoreactive analog photoleucine (photoLeu)
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custom assay reagents
Ubiquitin(-like) (e.g. Ub, Nedd8, SUMO, etc.) assay reagents with various modifications (unnatural amino acids, peptides, tags, etc.)
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custom probes
Custom ubiquitin(-like) probes with various C-terminal warheads (e.g. VME= vinylmethyl ester, PA = propagylamide, VS= vinyl sulfone, Dha= dehydroalanine) and N-terminal tags (e.g. TAMRA, Cy5, biotin).
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custom peptides
Our UbiQ-PEP™ service provides isopeptide linked Ub-polypeptide conjugates with a range of modifications to meet your research needs.