Ub-AMC
a quenched, fluorescent substrate for ubiquitin proteases
Additional information
| Weight | 0.05 kg |
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| sample preparation | For detailed sample preparation see product sheet. |
| regulatory statement |
€230.00
- Description
- Additional information
- references
Description
Ub-AMC (UbiQ-001) is a quenched, fluorescent substrate for ubiquitin proteases. Cleavage of the amide bond between the C-terminal glycine of ubiquitin and 7-amido-4-methylcoumarin (AMC) results in an increase in AMC fluorescence at 460 nm (Exc. 380 nm).
Additional information
| Weight | 0.05 kg |
|---|---|
| aliquot size | |
| bulk | |
| Applications | |
| target | |
| source | |
| shipping | |
| purity | |
| molecular weight | |
| storage | |
| sample preparation | For detailed sample preparation see product sheet. |
| regulatory statement |
Dang, L.C., et al. Kinetic and mechanistic studies on the hydrolysis of ubiquitin C-terminal 7-amido-4-methylcoumarin by deubiquitinating enzymes. Biochemistry. 37, 1868-1879 (1998). http://www.ncbi.nlm.nih.gov/pubmed/9485312