LRRASLG-GG-H2B(113-125) K120(Ub)
an H2B(113-125) peptide which is modified at K120 via a native isopeptide bond with ubiquitin; modified on the N-terminus with a PKA (cAMP-dependent Protein Kinase) sequence: LRRASLG
Additional information
| Weight | 0.005 kg |
|---|---|
| Applications | |
| target | |
| source | |
| shipping | |
| purity | |
| molecular weight | |
| storage | Powder at −20°C; buffered solution at −80°C. Please avoid multiple freeze/thaw cycles. |
| sample preparation | For detailed sample preparation see product sheet. |
| regulatory statement | |
| aliquot size |
€300.00
- Description
- Additional information
- references
Description
UbiQ-332 is based on an H2B(113-125) peptide which is modified at K120 via a native isopeptide bond with ubiquitin (Ub); modified on the N-terminus with a PKA (cAMP-dependent Protein Kinase) sequence: LRRASLG; a Gly-Gly linker is used to create extra space between the PKA and H2B peptide sequence. It can be used as a substrate for ubiquitin proteases, to investigate mechanism of binding and recognition by proteins that contain ubiquitin-associated domains or ubiquitin-interacting motifs (UIMs) and as antigen for immunizations.
Additional information
| Weight | 0.005 kg |
|---|---|
| Applications | |
| target | |
| source | |
| shipping | |
| purity | |
| molecular weight | |
| storage | Powder at −20°C; buffered solution at −80°C. Please avoid multiple freeze/thaw cycles. |
| sample preparation | For detailed sample preparation see product sheet. |
| regulatory statement | |
| aliquot size |
El Oualid, F., et al. Chemical Synthesis of Ubiquitin, Ubiquitin-Based Probes, and Diubiquitin. Angewandte Chemie Int. Ed. 49, 10149-10153 (2010).
http://www.ncbi.nlm.nih.gov/pubmed/21117055