LRRASLG-GG-H2B(113-125) K120(Ub)

an H2B(113-125) peptide which is modified at K120 via a native isopeptide bond with ubiquitin; modified on the N-terminus with a PKA (cAMP-dependent Protein Kinase) sequence: LRRASLG

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code UbiQ-332 Category Tag
product UbiQ-332 Category Tag

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Weight 0.005 kg
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Description

UbiQ-332 is based on an H2B(113-125) peptide which is modified at K120 via a native isopeptide bond with ubiquitin (Ub); modified on the N-terminus with a PKA (cAMP-dependent Protein Kinase) sequence: LRRASLG; a Gly-Gly linker is used to create extra space between the PKA and H2B peptide sequence. It can be used as a substrate for ubiquitin proteases, to investigate mechanism of binding and recognition by proteins that contain ubiquitin-associated domains or ubiquitin-interacting motifs (UIMs) and as antigen for immunizations.

Additional information

Weight 0.005 kg
Applications

, , ,

target

source

shipping

purity

molecular weight

storage

sample preparation

For detailed sample preparation see product sheet.

regulatory statement

aliquot size

El Oualid, F., et al. Chemical Synthesis of Ubiquitin, Ubiquitin-Based Probes, and Diubiquitin. Angewandte Chemie Int. Ed. 49, 10149-10153 (2010).
http://www.ncbi.nlm.nih.gov/pubmed/21117055