news - UbiQ

our blog

25 November 2025

New activity-based probes for deubiquitinating enzymes

Here we would like to introduce Biotin-Ahx-Ub-MTC (UbiQ-378) as a new type of activity-based probe for deubiquitinating enzymes (DUBs). Reported recently by Chanda et al., it contains a C-terminal...

14 July 2025

Poster prize award at the GRK2243 Symposium Understanding Ubiquitylation

We congratulate Dr Cara Ellison from the University of Oxford with the Poster Prize award at the GRK2243 Symposium Understanding Ubiquitylation: From Molecular Mechanisms to Disease 2025, in Würzburg (Germany).

16 May 2025

Live cell delivery of ubiquitin reagents by bead loading

We present a new protocol for intracellular delivery of our reagents (Figure 1). In protocol P010, (also in our resource download center), we outline a...

8 October 2024

First Poster Prize award at the EMBO ubiquitin conference

We congratulate Dr Jason Collins from the National Institute of Dental and Craniofacial Research / NIH (Bethesda, USA) with the First Poster Prize award at the 2024 EMBO ubiquitin conference in Cavtat.

Jason...

27 June 2023

Poster Prize awardees at the Biochemical Society conference in Edinburgh

We congratulate the Poster Prize awardees at last week's Deubiquitylases and Ubl-proteases conference of the Biochemical Society: well done to Benjamin Foster, Joana Gomes Neto, Alicia Cordova-Perez and Kim Wendrich.

June 19 – 21, 2023, Edinburgh, UK

3 March 2023

Launch of four new activity-based probes for deubiquitinating enzymes

We present four new HA-tagged activity-based probes for deubiquitinating enzymes (DUBs). The HA peptide sequence (YPYDVPDYA) allows for the sensitive identification or purification of DUBs by anti-HA antibodies and/or anti-HA-agarose. The HA tag is separated from...

21 February 2023

Moving our offices & laboratories.

We are happy and proud to announce that we have moved our office and labs to a brand new building at Science Park 301, just a five minutes walk from our old laboratories in the...

where to meet us

14 July 2025

Australian Ubiquitin Summit 2025

November 20 - 23, 2025 in Lorne, Australia

Lorne Ubiquitin - The Australia Ubiquitin Summit, 2025

Contact: Farid El Oualid (CSO, attending the conference) and Alfred Nijkerk (CEO, sponsorship)

28 March 2025

Innovation For Health 2025

April 3, 2025, Rotterdam, the Netherlands

Innovation For Health 2025

Contact: Alfred Nijkerk (CEO)

24 January 2025

Symposium Understanding Ubiquitylation

June 2 - 4, 2025, Würzburg, Germany

GR K2243 Symposium Understanding Ubiquitylation: From Molecular Mechanisms to Disease, 2025

Contact: Farid El Oualid (CSO) and Alfred Nijkerk (CEO) (sponsorship)

19 July 2024

International Plant Proteostasis Conference

September 17 - 20, 2024, Vienna, Austria

International Plant Proteostasis Conference 2024

Contact: Farid El Oualid (CSO) (sponsorship)

11 April 2024

EMBO conference on Ubiquitin

September 27 - October 1, 2024 Cavtat, Croatia

Ubiquitin and ubiquitin-like proteins in health and disease.

Contact: Alfred Nijkerk (CEO)

8 February 2024

2nd Severo Ochoa Conference

June 24 - 25, 2024 Bilbao, Spain

2nd Severo Ochoa Conference: Ligating the Ubiquitin Family; Physiology, Disease, and Future Directions June 2024

Contact: Farid El Oualid (CSO) (sponsorship)

6 February 2024

Ubiquitin & Friends Symposium

May 2 - 3, 2024 Vienna, Austria

Ubiquitin & Friends Symposium May 2024

Contact: Farid El Oualid (CSO) (sponsorship)

our publications

26 November 2025

Deubiquitinases regulate cleavage and stability of ubiquitin-fused ribosomal proteins via catalytic and non-catalytic activities

UbiQ is proud to have contributed to research just reported in Molecular Cell. This collaborative research between New York University School of Medicine (project leader: Tony T. Huang), UbiQ and the...

1 August 2025

USP1/UAF1 targets polyubiquitinated PCNA with an exo-cleavage mechanism

UbiQ is proud to have contributed to this paper in Nature Communications, describing our scientific collaboration on USP1 and PCNA with the Netherlands Cancer Institute. If you are interested in DNA damage...

16 January 2023

Characterization of the Ubiquitin and ISG15 Deconjugase Activity of SARS-CoV-1 and SARS-CoV-2 Papain-Like Protease

UbiQ is proud to have contributed a chapter to the Methods in Molecular Biology book series (MIMB,volume 2591), together with scientists at the University of Texas Health...

23 August 2022

Catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6

UbiQ is proud to have been part of a major collaborative research project focused on studying the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6 and whose results have been published in Nature Communications 2022,...

29 March 2022

Collaborative research looks into the (essential) roles of ubiquitin proteases and ubiquitin conjugation in Leishmania parasites

Poster presentation by Daniel Harris at the 21st Royal Society of Chemistry - Medicinal Chemistry Symposium (13 - 15 September 2021, Cambridge UK).

Title: A ubiquitin activating enzyme as a novel therapeutic target for leishmaniasis.

Daniel Harris...

18 November 2020

Anti–COVID-19 Drug Design by targeting a molecular scissor of Ubiquitin and ISG15

UbiQ is proud to have been part of a major collaboration reported recently by Rut et al. in Science Advances (2020, 6, eabd4596) describing the activity profiling and crystal structures of inhibitor...

9 July 2020

Leishmania differentiation requires ubiquitin conjugation mediated by a UBC2-UEV1 E2 complex

We are proud to present collaborative research (Burge et al. PLoS Pathogens 2020, 16: e1008784), between the University of York, University of Glasgow and UbiQ that describes the (essential) roles of ubiquitin...