news
our blog
Live cell delivery of ubiquitin reagents with peptide L17ER4 (UbiQ-381)
We would like to highlight another new reagent and protocol for intracellular delivery of ubiquitin(-like) reagents (Figure 1) based on work by Giancola et al. from the lab of Prof....
Best EMCR talk award at the Australian Ubiquitin Summit in Lorne
As a proud sponsor of the Best Early and Mid-Career Researchers Talk award at the Australian Ubiquitin Summit, we congratulate Mengying with her well deserved award for her presentation titled:...
New activity-based probe for deubiquitinating enzymes
Here we would like to introduce Biotin-Ahx-Ub-MTC (UbiQ-378) as a new type of activity-based probe for deubiquitinating enzymes (DUBs). Reported recently by Chanda et al., it contains a C-terminal...
Poster prize award at the GRK2243 Symposium Understanding Ubiquitylation
We congratulate Dr Cara Ellison from the University of Oxford with the Poster Prize award at the GRK2243 Symposium Understanding Ubiquitylation: From Molecular Mechanisms to Disease 2025, in Würzburg (Germany).
Live cell delivery of ubiquitin reagents by bead loading
We present a new protocol for intracellular delivery of our reagents (Figure 1). In protocol P010, we outline a straightforward, mild and cost-effective method for the application of ubiquitin(-like) reagents...
First Poster Prize award at the EMBO ubiquitin conference
We congratulate Dr Jason Collins from the National Institute of Dental and Craniofacial Research / NIH (Bethesda, USA) with the First Poster Prize award at the 2024 EMBO ubiquitin conference in Cavtat. Jason...
Poster Prize awardees at the Biochemical Society conference in Edinburgh
We congratulate the Poster Prize awardees at last week's Deubiquitylases and Ubl-proteases conference of the Biochemical Society: well done to Benjamin Foster, Joana Gomes Neto, Alicia Cordova-Perez and Kim Wendrich. June 19 – 21, 2023, Edinburgh, UK
where to meet us
Australian Ubiquitin Summit 2025
November 20 - 23, 2025 in Lorne, Australia Lorne Ubiquitin - The Australia Ubiquitin Summit, 2025 Contact: Farid El Oualid (CSO, attending the conference) and Alfred Nijkerk (CEO, sponsorship)
Innovation For Health 2025
April 3, 2025, Rotterdam, the Netherlands Innovation For Health 2025 Contact: Alfred Nijkerk (CEO)
Symposium Understanding Ubiquitylation
June 2 - 4, 2025, Würzburg, Germany GRK2243 Symposium Understanding Ubiquitylation: From Molecular Mechanisms to Disease, 2025 Contact: Farid El Oualid (CSO) and Alfred Nijkerk (CEO) (sponsorship)
International Plant Proteostasis Conference
September 17 - 20, 2024, Vienna, Austria International Plant Proteostasis Conference 2024 Contact: Farid El Oualid (CSO) (sponsorship)
EMBO conference on Ubiquitin
September 27 - October 1, 2024 Cavtat, Croatia Ubiquitin and ubiquitin-like proteins in health and disease. Contact: Alfred Nijkerk (CEO)
2nd Severo Ochoa Conference
June 24 - 25, 2024 Bilbao, Spain 2nd Severo Ochoa Conference: Ligating the Ubiquitin Family; Physiology, Disease, and Future Directions June 2024 Contact: Farid El Oualid (CSO) (sponsorship)
Ubiquitin & Friends Symposium
May 2 - 3, 2024 Vienna, Austria Ubiquitin & Friends Symposium May 2024 Contact: Farid El Oualid (CSO) (sponsorship)
our publications
Deubiquitinases regulate cleavage and stability of ubiquitin-fused ribosomal proteins
UbiQ is proud to have contributed to research just reported in Molecular Cell. This collaborative research between New York University School of Medicine (project leader: Tony T. Huang), UbiQ and the...
USP1/UAF1 targets polyubiquitinated PCNA with an exo-cleavage mechanism
UbiQ is proud to have contributed to this paper in Nature Communications, describing our scientific collaboration on USP1 and PCNA with the Netherlands Cancer Institute. If you are interested in DNA damage...
Characterization of the Ubiquitin and ISG15 Deconjugase Activity of SARS-CoV-1 and SARS-CoV-2 Papain-Like Protease
UbiQ is proud to have contributed a chapter to the Methods in Molecular Biology book series (MIMB,volume 2591), together with scientists at the University of Texas Health...
Catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6
UbiQ is proud to have been part of a major collaborative research project focused on studying the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6 and whose results have been published in Nature Communications. Uba6 is...
Collaborative research looks into the (essential) roles of ubiquitin proteases and ubiquitin conjugation in Leishmania parasites
Poster presentation by Daniel Harris at the 21st Royal Society of Chemistry - Medicinal Chemistry Symposium (13 - 15 September 2021, Cambridge UK). Title: A ubiquitin activating enzyme as a novel therapeutic target for leishmaniasis. Daniel Harris...
Anti–COVID-19 Drug Design by targeting a molecular scissor of Ubiquitin and ISG15
UbiQ is proud to have been part of a major collaboration reported recently by Rut et al. in Science Advances (2020, 6, eabd4596) describing the activity profiling and crystal structures of inhibitor...
Leishmania differentiation requires ubiquitin conjugation mediated by a UBC2-UEV1 E2 complex
We are proud to present collaborative research (Burge et al. PLoS Pathogens 2020, 16: e1008784), between the University of York, University of Glasgow and UbiQ that describes the (essential) roles of ubiquitin...