Biotin-Ahx-Ub pThr12

ubiquitin, phosphorylated on Thr12, labeled on the N-terminus with biotin

productsheet

code UbiQ-093 Category Tags ,
product UbiQ-093 Category Tags ,

Additional information

Weight 0.005 kg
aliquot size

Applications

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sample preparation

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regulatory statement

Clear

200.00

Description

UbiQ-093 is ubiquitin that is phosphorylated on Thr12. Phosphoproteomic studies have identified several phosphorylated sites in ubiquitin, among them pThr12. It is labeled on the N-terminus with biotin; an aminohexanoic acid (Ahx) linker is used to create extra space between the biotin and Ub protein for efficient access of biotin binding entities. It has been made by total chemical synthesis and is therefore well-defined in terms of biotin and pThr site and incorporation efficiency (100%).

Additional information

Weight 0.005 kg
aliquot size

Applications

, , ,

source

shipping

purity

molecular weight

storage

sample preparation

For detailed sample preparation see product sheet.

regulatory statement

Bennetzen et al. Mol Cell Proteomics 2010, 9, 1314.
https://www.ncbi.nlm.nih.gov/pubmed/20164059

Bian et al. J Proteomics 2014, 96, 253.
https://www.ncbi.nlm.nih.gov/pubmed/24275569

Kettenbach et al. Sci Signal, 2011, 4, rs5.
https://www.ncbi.nlm.nih.gov/pubmed/21712546

Sharma et al. Cell Rep 2014, 8, 1583.
https://www.ncbi.nlm.nih.gov/pubmed/25159151

Zhou et al. J Proteome Res 2013, 12, 260.
https://www.ncbi.nlm.nih.gov/pubmed/23186163

El Oualid et al. Angew Chem Int Ed 2010, 49, 10149.
https://www.ncbi.nlm.nih.gov/pubmed/21117055