![UbiQ-061](https://ubiqbio.com/wp-content/uploads/2022/03/UbiQ-061.png)
H2A(113-127) K120Ub
an H2A(113-127) peptide which is modified at K120 via a native isopeptide bond with ubiquitin
Additional information
Weight | 0.05 kg |
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aliquot size | |
Applications | |
target | |
source | |
shipping | |
purity | |
molecular weight | |
storage | upon arrival powder at −20°C, solution at −80°C. Please avoid multiple freeze/thaw cycles. |
sample preparation | For detailed sample preparation see product sheet. |
regulatory statement |
€250.00
- Description
- Additional information
- references
Description
UbiQ-061 is based on an H2A(113-127) peptide which is modified at K120 via a native isopeptide bond with ubiquitin (Ub). It can be used as a substrate for ubiquitin proteases, to investigate mechanism of binding and recognition by proteins that contain ubiquitin-associated domains or ubiquitin-interacting motifs (UIMs) and as antigen for immunizations.
Additional information
Weight | 0.05 kg |
---|---|
aliquot size | |
Applications | |
target | |
source | |
shipping | |
purity | |
molecular weight | |
storage | upon arrival powder at −20°C, solution at −80°C. Please avoid multiple freeze/thaw cycles. |
sample preparation | For detailed sample preparation see product sheet. |
regulatory statement |
F. El Oualid et al.
El Oualid, F., et al. Chemical Synthesis of Ubiquitin, Ubiquitin-Based Probes, and Diubiquitin. Angewandte Chemie Int. Ed. 49, 10149-10153 (2010).
http://www.ncbi.nlm.nih.gov/pubmed/21117055
Faesen et al.
Faesen, A.C., et al. The Differential Modulation of USP Activity by Internal Regulatory Domains, Interactors and Eight Ubiquitin Chain Types. Chem. Biol. 18, 1550-1561 (2011).
http://www.ncbi.nlm.nih.gov/pubmed/22195557
I. Dikic et al.
Dikic, I., et al. Ubiquitin-binding domains – from structures to functions. Nat. Rev. Mol. Cell. Biol. 10, 659-671 (2010).
http://www.ncbi.nlm.nih.gov/pubmed/19773779
J. D. F. Licchesi et al.
Licchesi, J.D., et al. An ankyrin-repeat ubiquitin-binding domain determines TRABID’s specificity for atypical ubiquitin chains. Nat. Struct. Mol. Biol. 19, 62-71 (2012).
http://www.ncbi.nlm.nih.gov/pubmed/22157957