K382 Ub-p53(357-389)-FP
UbiQ-042 is a class II fluorescence polarization HTS reagent based on the C-terminal p53 peptide sequence 357-389, conjugated at Lys382 to Ub via a native isopeptide bond.
Additional information
| Weight | 0.005 kg |
|---|---|
| aliquot size | |
| Applications | |
| target | |
| source | |
| shipping | |
| purity | |
| molecular weight | |
| storage | −20°C; buffered solution at −80°C. Please avoid multiple freeze/thaw cycles. |
| sample preparation | For detailed sample preparation see product sheet. |
| regulatory statement |
€300.00
- Description
- Additional information
- references
Description
UbiQ-042 (K382 Ub-p53(357-389)-FP) is a class II fluorescence polarization HTS reagent based on the C-terminal peptide sequence 357- 389 of p53. The peptide is modified on the N-terminus with a TAMRA (5-carboxytetramethylrhodamine) dye and conjugated at Lys382 to Ub via a native isopeptide bond. UbiQ-042 contains a PGGS motif (aa 359-362), which is important for USP7 binding.
Additional information
| Weight | 0.005 kg |
|---|---|
| aliquot size | |
| Applications | |
| target | |
| source | |
| shipping | |
| purity | |
| molecular weight | |
| storage | −20°C; buffered solution at −80°C. Please avoid multiple freeze/thaw cycles. |
| sample preparation | For detailed sample preparation see product sheet. |
| regulatory statement |
Geurink, P.P., et al. A general chemical ligation approach towards isopeptide-linked ubiquitin and ubiquitin-like assay reagents. ChemBiochem 13, 293-297 (2012).
http://www.ncbi.nlm.nih.gov/pubmed/22213387