custom ubiquitin reagents
We offer a tailored and chemical approach to producing specific ubiquitinated conjugates. This allows researchers to design reagents that are not readily available by traditional (biological) methods. Custom ubiquitin synthesis can be used to develop specific probes to study the (de)ubiquitination process. This is important to gain insight into enzyme-substrate interactions that are critical for function and thus for developing targeted therapies. Finally, besides their application as advanced assay reagents (for high-throughput screening), ubiquitin conjugates are also of great value for antibody development.
Explore the forefront of ubiquitin research and drug discovery with UbiQ’s innovative reagents – discover more today
Our total synthesis based technology platform allows us to prepare a wide range of ubiquitin and ubiquitin-like protein reagents:
assay reagents, probes, chains and ubiquitinated peptides (substrate context)
ubiquitin and ubiquitin-like proteins (e.g. Nedd8, SUMO, ISG15)
electrophiles (warheads), affinity and detection tags, unnatural amino acids
price & timelines
prices are on a project basis and bulk preparation (starting at 2 mg)
- 6 – 8 weeks lead time for most projects
references
over the years, we have developed a large number of custom probes, assay reagents and ubiquitinated peptides for the top 10 Pharma, biotechs and academic institutions: DUB focused assay reagents and probes, HTRF assays, custom incorporation of electrophiles, reagents with substrate context
we also co-developed an antibody for yeast K123 Ub-H2B
please have a look at our resource download center for protocols and (literature) background
want to know more?
please contact us at sales@ubiqbio.com to discuss your project and/or receive a detailed quote.
connect with us
We encourage you to leave your details through our online form to fully harness the potential of custom ubiquitin synthesis for your research and development projects. Engage with our team to explore how our custom reagents service can advance your studies in molecular biology and drug discovery.