H2B (113-125) K120 Ub

an H2B(113-125) peptide, monoubiquitinated at K120 via a native isopeptide bond

productsheet

Additional information

Weight 0.05 kg
aliquot size

bulk

Applications

, , ,

target

source

shipping

purity

molecular weight

storage

upon arrival powder at −20°C, solution at −80°C. Please avoid multiple freeze/thaw cycles.

sample preparation

For detailed sample preparation see product sheet.

regulatory statement

Clear
View cart

250.00

Description

UbiQ-062 is an H2B(113-125) peptide which is monoubiquitinated at K120 via a native isopeptide bond.
It can be used as a substrate for ubiquitin proteases, to investigate mechanism of binding and recognition by proteins that contain ubiquitin-associated domains or ubiquitin-interacting motifs (UIMs) and as antigen for immunizations.

Additional information

Weight 0.05 kg
aliquot size

bulk

Applications

, , ,

target

source

shipping

purity

molecular weight

storage

upon arrival powder at −20°C, solution at −80°C. Please avoid multiple freeze/thaw cycles.

sample preparation

For detailed sample preparation see product sheet.

regulatory statement

F. El Oualid et al.
El Oualid, F., et al. Chemical Synthesis of Ubiquitin, Ubiquitin-Based Probes, and Diubiquitin. Angewandte Chemie Int. Ed. 49, 10149-10153 (2010).
http://www.ncbi.nlm.nih.gov/pubmed/21117055

Faesen et al.
Faesen, A.C., et al. The Differential Modulation of USP Activity by Internal Regulatory Domains, Interactors and Eight Ubiquitin Chain Types. Chem. Biol. 18, 1550-1561 (2011).
http://www.ncbi.nlm.nih.gov/pubmed/22195557

I. Dikic et al.
Dikic, I., et al. Ubiquitin-binding domains – from structures to functions. Nat. Rev. Mol. Cell. Biol. 10, 659-671 (2010).
http://www.ncbi.nlm.nih.gov/pubmed/19773779

J. D. F. Licchesi et al.
Licchesi, J.D., et al. An ankyrin-repeat ubiquitin-binding domain determines TRABID’s specificity for atypical ubiquitin chains. Nat. Struct. Mol. Biol. 19, 62-71 (2012).
http://www.ncbi.nlm.nih.gov/pubmed/22157957