H2A (113-127) K119 Ub

an H2A(113-127) peptide, monoubiquitinated at K119 via a native isopeptide bond

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Weight 0.05 kg
aliquot size

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For detailed sample preparation see product sheet.

regulatory statement

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Description

UbiQ-060 is an H2A(113-127) peptide which is monoubiquitinated at K119 via a native isopeptide bond.
It can be used as a substrate for ubiquitin proteases, to investigate the mechanism of binding and recognition by proteins that contain ubiquitin-associated domains or ubiquitin-interacting motifs (UIMs) and as an antigen for immunizations.

Additional information

Weight 0.05 kg
aliquot size

Applications

, , ,

target

source

shipping

purity

molecular weight

storage

sample preparation

For detailed sample preparation see product sheet.

regulatory statement

F. El Oualid et al.
El Oualid, F., et al. Chemical Synthesis of Ubiquitin, Ubiquitin-Based Probes, and Diubiquitin. Angewandte Chemie Int. Ed. 49, 10149-10153 (2010).
http://www.ncbi.nlm.nih.gov/pubmed/21117055

Faesen et al.
Faesen, A.C., et al. The Differential Modulation of USP Activity by Internal Regulatory Domains, Interactors and Eight Ubiquitin Chain Types. Chem. Biol. 18, 1550-1561 (2011).
http://www.ncbi.nlm.nih.gov/pubmed/22195557

I. Dikic et al.
Dikic, I., et al. Ubiquitin-binding domains – from structures to functions. Nat. Rev. Mol. Cell. Biol. 10, 659-671 (2010).
http://www.ncbi.nlm.nih.gov/pubmed/19773779

J. D. F. Licchesi et al.
Licchesi, J.D., et al. An ankyrin-repeat ubiquitin-binding domain determines TRABID’s specificity for atypical ubiquitin chains. Nat. Struct. Mol. Biol. 19, 62-71 (2012).
http://www.ncbi.nlm.nih.gov/pubmed/22157957