K13 Ub-PTEN(5-21)-FP

a class II fluorescence polarization DUB activity assay reagent based on the peptide sequence 5 – 21 of PTEN, which is monoubiquitinated on Lys13 and Lys289

productsheet

code UbiQ-030 Category
product UbiQ-030 Category

Additional information

Weight 0.005 kg
aliquot size

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source

human, synthetic

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For detailed sample preparation see product sheet.

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Description

UbiQ-030 (K13 Ub-PTEN(5-21)-FP) is a class II fluorescence polarization DUB activity assay reagent based on the peptide sequence 5 – 21 of PTEN, a tumor suppressor phosphatase which is monoubiquitinated on Lys13 and Lys289. Monoubiquitination of these sites is important for regulation of PTEN mediated tumor suppression and its nuclear import. The peptide is modified on the N-terminus with a 5-carboxytetramethylrhodamine and conjugated at Lys13 to Ub via a native isopeptide bond. See reference 4 (open access) in the product sheet for full experimental and analytical details.

Additional information

Weight 0.005 kg
aliquot size

Applications

,

target

source

human, synthetic

shipping

purity

molecular weight

sample preparation

For detailed sample preparation see product sheet.

regulatory statement